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姓名：高洁

职务职称：教授，博士生导师

性别：女

毕业院校及专业学位：浙江大学食品科学博士

所在部门：河北农业大学食品科技学院(d座1415室)

通讯地址：河北省保定市河北农业大学食品科技学院

邮政编码：071001

电子邮箱：

个人简介：

高洁，女，博士，教授，博导。2013年毕业于浙江大学食品科学专业，同年就职于中国cdc营养与健康所，2018年通过人才引进至河北农业大学食品科技学院工作，现任学院业务助理，生工系党支部书记、副主任。主持国家自然科学基金项目1项，河北省自然科学基金项目1项，河北省重点研发计划项目1项，河北大学引进人才项目1项，中国疾病预防控制中心基金2项，参与国家及省重点研发计划项目3项，生物农联合基金1项，河北省教改项目1项。发表国内外高水平学术论文40余篇。申请国家发明专利10项。河北省精品课程主讲人。

一、主要学术及社会兼职

中国食品科学技术学会青年委员会委员

中国食品科学技术学会益生菌分会理事

中国微生物学会酿造分会委员

河北省食品学会副秘书长

河北省食品学会青委会常务副主任兼秘书长

二、主讲课程及主要研究方向

1、主讲食品微生物学、益生菌与健康、益生菌与益生元等本科及研究生课程

2、主要研究方向为：乳酸菌、益生菌资源开发利用，发酵性能改善、肠道菌群调节功能研究等。

三、代表成果

1、论文

[1]jie gao, faizan ahmed sadig, yixin zheng, jinrong zhao, guoqing he*, and yaxin sang* biofilm-based delivery approaches and specific enrichment strategies of probiotics in the human gut [j]. gut microbes, 2022, 14(1).

[2]jie gao, xiyu li, jesus simal-gandara, guohua zhang*, jianbo xiao, faizan ahmed sadiq, yaxin sang*. probiotics in the dairy industry—advances and opportunities [j]. comprehensive reviews in food science and food safety, 2021, 20(4): 3937-82.

[3]jie gao, kemin mao, xianghong wang, si mi, mengqi fu, xiyu li, jianbo xiao, jesus simal-gandara, yaxin sang*. tibet kefir milk regulated metabolic changes induced by high-fat diet via amino acids, bile acids, and equol metabolism in human-microbiota-associated rats [j]. j agric food chem, 2021, 69(23): 6720-32.

[4]jie gao, qi li, yuwei liu, bing yang, faizan ahmed sadiqb, xiyu li, si mi, and yaxin sang*. immunoregulatory effect of lactobacillus paracasei vl8 exopolysaccharide on raw264.7 cells by nf-κb and mapk pathways [j]. journal of functional foods, 2022, 95.

[5] yuehong ji, kemin mao,jie gao*, bimal chitrakar1, faizan ahmed sadiq, zhongxuan wang, jiangna wu, chao xu, yaxin sang*. pear pomace soluble dietary fiber ameliorates the negative effects of high-fat diet in mice by regulating the gut microbiota and associated metabolites [j]. front nutr, 2022, 9: 1025511.

[6]yueyao wang, guifang tian, kemin mao, bimal chitrakar1, zhongxuan wang1, jie liu, xinzhong bai, yaxin sang*,jie gao*.effects of four cooking methods on flavor and sensory characteristics of scallop muscle [j]. front nutr, 2022, 9: 1022156.

[7] wenyi deng, guifang tian, zhongxuan wang, kemin mao, xiaohan liu, qiuyue ding, yaxin sang*,jie gao*. analysis of volatile components changes of ruditapes philippinarum during boiling by hs-gc-ims coupled with multivariate analyses [j]. aquaculture reports, 2022, 25.

[8]jie gao, gangqiang ding, qi li, lingxiao gong, jian huang, yaxin sang*. tibet kefir milk decreases fat deposition by regulating the gut microbiota and gene expression oflplandangptl4 in high fat diet-fed rats[j]. food research international, 2019, 121:278-287.

[9]kemin mao¹,jie gao¹xianghong wang, xiyu li, shuo geng, tuo zhang, faizan ahmed sadiq, yaxin sang*. bifidobacterium animalis subsp. lactis bb-12 has effect against obesity by regulating gut microbiota in two phases in human microbiota-associated rats [j]. front nutr, 2021, 8: 811619.

[10] xiyu li,jie gao, jesus simal-gandara, xianghong wang, giovanni caprioli, si mi, yaxin sang*. effect of fermentation by lactobacillus acidophilus ch-2 on the enzymatic browning of pear juice [j]. lwt, 2021, 147.

[11] mengqi fu, kemin mao,jie gao, xianghong wang, faizan ahmed sadiq, jiale li, yaxin sang*. characteristics of surface layer protein from lactobacillus kefiri hba20 and the role in mediating interactions with saccharomyces cerevisiae y8 [j]. int j biol macromol, 2022, 201: 254-61.

[12] mengqi fu, si mi, jinrong zhao, xianghong wang,jie gao, yaxin sang*. the interaction mechanism, conformational changes and computational simulation of the interaction between surface layer protein and mannan at different ph levels [j]. food chemistry, 2023, 405.

[13] shuo geng, tuo zhang,jie gao, xiyu li, bimal chitrakar, kemin mao, yaxin sang*. in vitro screening of synbiotics composed of lactobacillus paracasei vl8 and various prebiotics and mechanism to inhibits the growth of salmonella typhimurium [j]. lwt, 2023, 180.

[14]李佳乐,毛可敏,桑亚新,高洁*.雪莲菌颗粒形成机制研究进展中国食品学报[j].中国食品学报, 2021, 21(9):386-396

[15]丁钢强,高洁.中国居民营养的发展与挑战[j].中国食品学报, 2016, 16(7):1-6.

2、专利

[1]高洁，桑亚新，李希羽，纪月洪，付梦琪，李佳乐.一种促进雪莲菌增殖的复合添加剂:中国, zl202110500831.5. 2022-08-26.

[2]高洁，桑亚新，李佳乐.一株高加索酸奶乳杆菌hba20及其高产slp的方法:中国, zl202111121846.7. 2023-03-10.

[3]桑亚新，王向红，周畅，于文龙，高洁，刘卫华.一种柿子醋的制备方法:中国, 201910027195.1. 2019-01-11.

3、图书

孙静，高洁.婴幼儿喂养手册[m]. 2017，中国人口出版社,北京.